The anaesthetist >> Monitoring and vasoactive drugs

It is reasonable to assume that all patients for aortic aneurysm repair surgery will be monitored with the standard mandatory monitors, together with direct arterial pressure and central venous pressure monitoring (subject to the exigencies of the emergency situation for ruptured aneurysms). There is less agreement about the use of pulmonary artery flotation catheters and cardiac output monitors.

Table 19 shows the number of patients undergoing open elective aneurysm repair in whom a pulmonary artery flotation catheter was inserted.

Table 19. Intraoperative use of pulmonary artery flotation catheter
Pulmonary catheter Elective % Emergency % Not answered Total
Yes 8 2 2 1 1 11
No 370 98 217 99 52 639
Sub-total 378   219   53 650
Unknown 0   2   0 2
Not answered 56   43   1 100
Total 434   264   54 752

It would appear that at the time of this study very few anaesthetists thought that the use of pulmonary artery catheters was justified for either elective or emergency open aneurysm repair.

Table 20 shows the number of patients undergoing open aneurysm repair in whom it was reported that the cardiac output was measured.

Table 20. Intraoperative measurement of cardiac output
Cardiac output monitoring Elective % Emergency % Not answered Total
Yes 30 8 14 6 3 47
No 347 92 204 94 50 601
Sub-total 377   218   53 648
Unknown 0   2   0 2
Not answered 57   44   1 102
Total 434   264   54 752

In 10 of the cases (two were emergencies) a pulmonary artery flotation catheter was inserted and presumably was used for measuring the cardiac output by the thermodilution technique. The use of other techniques in 37 patients must reflect the increasing availability of non-invasive methods such as oesophageal Doppler devices and rebreathing devices. Overall, cardiac output was monitored in 7% (47/648) of patients.

Table 21 shows the numbers of patients who received inotropic drugs, defined as “drugs given for inotropic effect e.g. epinephrine, dobutamine”.

Table 21. Use of inotropes
Inotropes Elective % Emergency % Not answered Total
Yes 113 30 115 53 23 251
No 263 70 103 47 30 396
Sub-total 376   218   53 647
Unknown 1   2   0 3
Not answered 57   44   1 102
Total 434   264   54 752

Table 22 shows the numbers of patients who received vasoconstrictor drugs, defined as “…drugs ... given for vasoconstrictor effect e.g. metaraminol, phenylephrine, norepinephrine”.

Table 22. Use of vasoconstrictors
Vasoconstrictors Elective % Emergency % Not answered Total
Yes 258 69 142 66 34 434
No 117 31 74 34 18 209
Sub-total 375   216   52 643
Unknown 2   3   0 5
Not answered 57   45   2 104
Total 434   264   54 752

It is not surprising that vasoactive drugs were used frequently. Patients undergoing elective operation are likely to have received vasodilating anaesthetic techniques such as epidural anaesthesia, and emergency operation patients may have been hypotensive due to hypovolaemia or myocardial ischaemia. The logical use of vasoactive drugs requires knowledge of the effect of therapy on cardiac output and systemic vascular resistance, not just the effect on the blood pressure. It is of concern that whilst a total of 39% (251/647) of patients received inotropic drugs and 67% (434/643) of patients received vasoconstrictor drugs, the cardiac output was monitored in only 7% of patients. When cardiac output monitoring was not used, was the anaesthetist certain that the patient’s condition was being optimised with minimal effects on myocardial ischaemia?

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